Abstract: The principle of steel structure design is one of the main course in civil engineering. In the current context of innovation and entrepreneurship, in order to train civil engineering professionals in line with the needs of the industry as well as to improve students’ innovation and practical ability, teachers optimitze the course plan, enrich the course teaching content and improve the teaching means, it has formed project-oriented acurriculum system, built solid theoretical foundation, fostered independent learning, and strengthened the network auxiliary. The teaching reform of steel structure course integrated with the idea of innovation and entrepreneurship education can effectively strengthen students' practice ability and improve consciousness of innovation and entrepreneurship.