催化酯交换合成原戊酸正丁酯

Synthesis of tributyl orthovalerate by transesterification over catalyst

摘要: 在原戊酸三甲酯和正丁醇的酯交换反应中,分别以强碱NaOH、强酸HCI和固态碘作催化剂合成原戊酸正丁酯,结果表明:碘具有较好的催化效果和后处理提纯.通过进行多组实验,得出了该酯交换反应的最佳条件为n(原戊酸三甲酯)/n(正丁醇)=1:28、催化剂用量为反应物原戊酸三甲酯的4%、反应时间4h、反应温度为68-70℃(真空度:-0.09MPa),在此最佳条件下,原戊酸三甲酯的转化率达87.5%,原戊酸正丁酯的收率为82.6%,纯度比使用其他两种催化剂的要略高,达到98.3%.

Abstract: Tributyl orthovalerate was synthesized using trimethyl orthovalerate and normal butanol as reactants and I₂ as catalyst.With strong base NaOH and strong acid HCl as catalyst,this transesterification has fairly good catalysis effect and post-processing purification method through using I₂ as catalyst.The optimum reaction condition and result are as follows: with4% I₂ of trimethyl orthovalerate,and n(trimethyl orthovalerate)/n(normal butanol)=1:28,reacting at 68-70℃ (vacuum degree:-0.09MPa)for4h,conversion of trimethyl orthovalerate was 87.5% and the yield of tributyl orthovalerate was82.6%.Besides,the product purity can reach 98.3%.