吴浩楠,张帆,吴开志,等. 基于时空特征建模的肝肿瘤动态CEUS图像分类方法[J]. 南昌航空大学学报(自然科学版),2026,40(3):50-60. doi: 10.3969/j.issn.2096-8566.2026.03.005
引用本文: 吴浩楠,张帆,吴开志,等. 基于时空特征建模的肝肿瘤动态CEUS图像分类方法[J]. 南昌航空大学学报(自然科学版),2026,40(3):50-60. doi: 10.3969/j.issn.2096-8566.2026.03.005
WU Haonan,ZHANG Fan,WU Kaizhi,et al. A spatiotemporal feature modeling method for liver tumor classification in dynamic CEUS images[J]. Journal of Nanchang Hangkong University (Natural Sciences),2026,40(3):50-60. doi: 10.3969/j.issn.2096-8566.2026.03.005
Citation: WU Haonan,ZHANG Fan,WU Kaizhi,et al. A spatiotemporal feature modeling method for liver tumor classification in dynamic CEUS images[J]. Journal of Nanchang Hangkong University (Natural Sciences),2026,40(3):50-60. doi: 10.3969/j.issn.2096-8566.2026.03.005

基于时空特征建模的肝肿瘤动态CEUS图像分类方法

A Spatiotemporal Feature Modeling Method for Liver Tumor Classification in Dynamic CEUS Images

  • 摘要: 肝肿瘤良恶性分类是医学影像辅助诊断的重要研究方向。然而,动态对比增强超声(CEUS)图像具有时序长、关键事件稀疏及病灶区域小等特点,现有方法难以有效建模其时空特征。为此,本文提出一种基于时空特征建模的肝肿瘤CEUS图像良恶性分类方法。首先,利用时序变形注意力模块自适应选择关键参考帧,从而提升时序特征提取能力。其次,采用空间注意力机制强化病灶及周边区域特征表示。最后,采用时间注意力机制对每一帧分配权重,使模型专注于对分类最有影响的关键帧。结果表明,本文模型取得了84.2% 的准确率、84.1%的F1-score和90.9%的AUROC,均优于传统深度学习方法和其他时序建模方法。消融实验与统计检验验证了各模块的有效性。本文方法具有较高的分类精度和计算效率,为肝肿瘤的自动诊断提供了一种具有潜力的、可解释的辅助解决方案。

     

    Abstract: Classification of liver tumors into benign and malignant is an important research direction in computer-aided diagnosis for medical imaging. However, dynamic contrast-enhanced ultrasound (CEUS) images are characterized by long temporal sequences, sparse key events, and small lesion regions, making it challenging for existing methods to effectively model their spatiotemporal features. To address these limitations, this paper proposes a spatiotemporal feature modeling-based method for benign and malignant classification of liver tumors in dynamic CEUS images. First, a temporal deformable attention module is introduced to adaptively select key reference frames and enhance temporal feature extraction. Second, a spatial attention mechanism is employed to strengthen the representation of lesion regions and their surrounding tissues. Finally, a temporal attention mechanism assigns adaptive weights to individual frames, enabling the model to focus on the most informative frames for classification. Experimental results demonstrate that the proposed model achieves an accuracy of 84.2%, an F1-score of 84.1%, and an AUROC of 90.9%, outperforming conventional deep learning approaches and other temporal modeling methods. Ablation studies and statistical analyses further verify the effectiveness of the proposed modules. The proposed method achieves high classification accuracy and computational efficiency, providing a promising and interpretable auxiliary solution for the automatic diagnosis of liver tumors.

     

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