Abstract: In aerospace and nuclear power applications, the performance of conventional thermal protection coatings under extreme service conditions has encountered limitations. High-entropy alloys prepared by laser cladding have emerged as a promising candidate for high-temperature protective coatings owing to their outstanding comprehensive properties. For such coatings, oxidation-induced spallation constitutes the most prevalent failure mode, and their oxidation resistance plays a decisive role in determining actual service life. This paper systematically reviews recent advances in laser-cladded high-entropy alloy coatings for high-temperature oxidation resistance. The intrinsic micro-mechanisms responsible for the enhanced oxidation resistance of high-entropy alloy coatings via the addition of antioxidant elements, ceramic particles, and rare-earth oxides are analyzed in detail. Furthermore, prospects for the development, performance optimization, and future applications of oxidation-resistant laser-cladded high-entropy alloy coating systems are presented.