Abstract: The virtual simulation experimental technology is an important part of educational informatization. It has been widely used and developed rapidly in the field of higher education. According to the characteristics of experimental courses and practical courses of civil engineering, the importance of developing virtual simulation experiment teaching is analyzed. Based on the civil engineering experimental teaching demonstration center of Nanchang Hangkong University, 2 virtual simulation sub-experiments including low-cycle loading experiment of shear wall and beam-column joint, were designed with the background of “high-rise building structure”, a professional course of civil engineering. Advanced technologies such as virtual reality technology and interactive multimedia technology were effectively applied to this experimental teaching project to create a highly simulated experimental environment. It reflects the organic combination of subject foundation and development frontier, which is conducive to improve students' comprehensive ability and promote the cultivation of applied talents.