Abstract: In view of the phenomenon that information literacy evaluation of higher vocational students is fuzzy, polymorphic and difficult to be quantified, a fuzzy comprehensive evaluation model was used. Focusing on the four first-level indicators including information consciousness, information knowledge, information ability and information ethics, and the corresponding 11 second-level indicators and 35 third-level indicators, the information literacy evaluation indicator system was created. Based on the least square method, the combined weight vector of AHP-entropy weight method is obtained. According to the principle of maximum membership degree of multi-level fuzzy comprehensive evaluation, the comprehensive evaluation theory and system of information literacy of higher vocational students are formed. The results show that the information literacy of vocational college students is generally “good” rather than “average”, in which the information consciousness and information knowledge are both “good”, but the information ability and information morality are “average”.