Abstract: Aiming on the lightweight in the design process of the wheel loader boom, the optimization model based on volume design is established on the basis of analyzing the loading conditions of both the horizontal insertion and the vertical rising force. Based on the parametric design language APDL in ANSYS software, the topology optimization design of the boom is carried out by using the topology optimization module in ANSYS software, and the optimization results of the different volume design variables are obtained. Strength analysis was carried out on the optimized results. Under the condition of vertical rising force, the stress nephogram and the displacement deformation diagram before and after optimization were verified by sticking strain gauge and the results were in good agreement with the experimental results. The results show that all the performances of the optimized boom can meet the engineering design requirements, and the main design parameters can be determined on the basis of the optimized model. Thus the traditional design quality of the boom will be reduced and the purpose of energy saving will be achieved.