Abstract: This paper analyzes the problems existing in the cooperation between universities and enterprises, and expounds the necessity of the cooperation between universities and enterprises.Taking the metal materials Engineering major of Nanchang Hangkong University as the example, an innovative model of “three three five” industry-university-research cooperation was explored through multiple channels. That is, a three-level platform for industry-university-research cooperation has been established, three types of research cooperation have been carried out, and five supporting mechanisms have been developed. At the same time, the achievements of industry-university-research cooperation have been shared, providing useful exploration and reference for industry-university-research cooperation and talent training of materials majors.