Abstract: College mathematics education plays a very important role in the quality education of college students. This article analyzes the problems existing in the teaching process of college mathematics courses, and explores the problems of teaching reform according to the current situation of college mathematics teaching. First of all, it proposes online and offline characteristic teaching with individual students as the core and driven by related projects. Secondly, in the process of university mathematics teaching, we should pay attention to the scientific assessment and evaluation mechanism of process assessment and feedback. Finally, through the creation of a “three-three system” teaching model and a training model of “use competition to promote teaching and use competition to promote learning”, students’ comprehensive abilities will be cultivated. The reform of college mathematics-related courses is conducive to the implementation and popularization of the overall quality education of college students in colleges and universities, and is of great significance to comprehensively improving college students’ logical thinking ability and innovation and pioneering ability.