Abstract: The dispersion of MoSi₂ particles has a very important influence on the structure and properties of MoSi₂ based composites. In this paper, mechanical stirring and sedimentation methods are used to study the effect of sodium dodecyl sulfate (SDS) on the dispersion of MoSi₂ particles. The MoSi₂ powders were characterized by XRD, Scanning electron microscope and Zeta potentiometer. The results show that the dispersion conditions of sodium dodecyl sulfate (SDS) dispersant concentration, solid-liquid ratio, and dispersion time have a great influence on the dispersibility of MoSi₂ particles. SDS has strong adsorption capacity and uniform dispersion on MoSi₂ powder. The particle size of the dispersed MoSi₂ powder is between 0.2 and 0.6 μm, maintaining the dispersion and stability of the suspension. In addition, the preferred dispersion time of the dispersed MoSi₂ powder prepared in this work is 6 h, the solid-liquid ratio is 1:80, and the SDS concentration is 1.6 g/L.