Abstract: In recent years, the researches about Lab on a chip have got rapid development. The emergence of microfluidic chip has pushed the microfluidics and nanofluidics control system to a new level. Due to the significant advantages which microfluidic technology shows in sample consumption, analysis speed, operating costs and integration compared with traditional method, it has achieved widely applications in many fields, such as chemical synthesis, micro and nano materials preparation, cell analysis, drug screening and so on. Microfluidic crystallization as an important part of Lab on a chip, it provides a new platform for the research of crystallization process. In this paper, the characteristics and types of microfluidic crystallization chips are summarized, and the latest applications progress of microfluidic chip in crystallization research are also summarized. In the end, the developing prospects of microfluidics crystallization are prospected.