Abstract: The B2 tower of Shanglian Business Center, which adopts the reinforced concrete frame-core wall structural system, is a high-rise building exceeding the code's B-level height requirement. In this paper, SAUSAGE software is applied to create the structural numerical model, in which columns and beams are simulated by fiber beam elements, and shear walls are simulated by shell elements. Then the elastic-plastic time-history analysis on the structure under the rare earthquake is conducted. The results show that, under rare earthquake, only a few coupling beams are slightly damaged, and nearly all the shear walls and frames are free of damage. The structure deformation meets the requirements in technical specification for concrete structures of tall buildings. The overall structure has good mechanical performance and satisfies the performance-based seismic design goal.