Abstract: The influences of tensile strain rate and temperature on the interfacial properties of multilayer graphene are investigated by using the classical molecular dynamics (MD) simulation method. The results show that the interfacial strength increases with the increase of the tensile strain rate. However, when the loading rate is increased to 1e10 s^-1, the interfacial strength tends to be stable. In addition, the study also shows that the interfacial strength increases with the increase of temperature, but when the temperature reaches 350 K, the interfacial strength decreases, which is due to the temperature effect of the thermal expansion coefficient of multi-layer graphene. Moreover, the parameters of the cohesive zone model of interlayer interfaces in the multilayer graphene are obtained based on the MD results.