Abstract: To investigate the effects of the aluminum-titanium (Al+Ti) content and solution temperature on the grain uniformity and mechanical properties of GH4738 alloy, this study employed differential scanning calorimetry (DSC), optical microscopy (OM), and scanning electron microscopy (SEM) were employed to investigate the γ′ phase resolution temperature of GH4738 alloy with different (Al+Ti) content, its grain size uniformity after solution treatment at various temperatures ranging from 1030 to 1050 ℃, and its 760 ℃ tensile strength after solution treatment at 1040 ℃, stabilization treatment and aging treatment. The results reveal that with the increase of (Al+Ti) content, the resolution temperature of γ′ phase gradually rises. As the solution temperature increases, a certain proportion of coarse grains begin to emerge in the alloy, and the grain size gradually becomes uneven. The higher (Al+Ti) content is, the higher the solution temperature at which coarse grains appear is. 760 ℃ tensile strength of the alloy gradually rises with (Al+Ti) content increasing. The present work reveals (Al+Ti) content influences the solution treatment temperature and mechanical properties of GH4738 alloy. In engineering applications, an appropriate solution treatment temperature can be selected based on the different (Al+Ti) content of GH4738 alloy to obtain the desired microstructure and mechanical properties.