Abstract: After long-term working, passenger and freight rail transit vehicles may suffer localized corrosion or even rust wear,posing a huge threat to the structure service safety. In order to study the influence of corrosion depth on the fatigue strength of vehicle body structures, fatigue tests were conducted on the specimens with different corrosion depths from existing vehicles to obtain the fatigue limits. The relationship between corrosion depth and fatigue limit was studied based on simulation calculation and High-Goodman fatigue limit diagram. The results show that the failure mode of corrosion parts is uniform corrosion and local pitting. The median fatigue limit stresses of specimens with different corrosion depth show no obvious differences, which is about 65% of the median fatigue limit stress of specimens without corrosion. The fatigue failures of corrosion specimens all originate from pitting. The safety fatigue boundary of High-Goodman may be triggered when the corrosion depth of specimensreaches 30%. While, the simulation calculation boundary may be triggered when the corrosion depth exceeds 50%, leading to fatigue failure hazards to the service safety of vehicle structure.