Abstract: Adhesive failure of pressure-sensitive adhesive (PSA) will cause many quality problems. In order to study the influence of release film on adhesive tape failure, five release films and 3M acrylic PSA tape were selected as the research objects. The release films were heat-treated at 50 ℃ for 12~48 h and at 40~70 ℃ for 24 h, respectively, and then the peel strength change of the cooperative PSA tape after aging was investigated with the increase of heat treatment time of the release films. The effect of the release films after different heat treatment on the peel strength retention rate of the PSA tape was discussed. The results indicate that the heat treatment of baking the selected silicone/nano release film at 50 ℃ for 24 h can avoid the sharp decline in the peel strength of the cooperative PSA tape after damp-heat aging. The results are of great significance for the practical application of PSA tapes.