Abstract: Erosion wear of solid particles is the main reason for the wall wear and even failure of liquid pipeline. In this work, the erosion wear distribution of elbow under different influence factors was studied based on computational fluid dynamics (CFD) method. The results show that the prediction results based on DNV erosion model are in accordance with the experimental values. Furthermore, the erosion wear distribution of elbow under different solid particle properties was studied based on the DNV model. The results show that with the particle diameter increased from 10 µm to 200 µm, the maximum wear rate first drops and then rises. When the particle mass flow rate ranges from 0.02 to 0.20 kg/s, the maximum wear rate grows linearly with the increase of particle mass flow rate. With the particle shape coefficient enhanced from 0.2 to 1.0, the maximum wear rate first increases and then decreases. The research results can provide a theoretical support for the practical engineering application.