Abstract: Based on the finite element software ABAQUS and the 3D crack propagation analysis software Franc3D, the 3D fatigue crack growth of the center hole in a turbine disk is analyzed. Firstly, the surface crack growth of plate specimen is simulated, and the accuracy of the numerical simulation of the crack growth stress intensity factor (SIF) is verified by comparing the Gross/Brown theoretical model given in the manual. Then, for a turbofan engine's turbine disk, the stress intensity factors and the 3D fatigue crack growth life of initial defects are calculated for different turbine disk rim equivalent stresses as well as speeds. Finally, the influence of the difference of engine loads on the SIF and the fatigue crack propagation life is discussed. The results show that, in the case of the same crack length, the SIF increases with the increase of turbine disk rim's equivalent stresses and rotational speeds. The larger load is, the shorter fatigue life is, and the longer crack is, the greater influence is. It provides a reference for 3D crack growth calculation and life evaluation.