Abstract: The effect of strata subsidence on the mechanical behavior of buried pipelines was studied. Based on large deformation theory of thin shell and pipeline-soil interaction, strain response of X65 pipelines with no suspension under strata subsidence was simulated. The effect of key parameters on the mechanical behavior of buried pipelines were studied, including strata subsidence quantity, wall thickness, buried depth and soil properties. The results show that bending deformation and axial strain of buried pipelines increase with the subsidence quantity, but they decrease with wall thickness of the pipeline increasing. When the cohesion of the overlaying soil is bigger, the bending deformation of pipelines decreases with the buried depth increasing. But it increases with the buried depth increasing when the cohesion of the overlaying soil is smaller. Poisson's ratio of the soil has a small effect on the bending deformation and axial strain. Bending deformation and axial strain of buried pipelines increase with the increase of elastic modulus and cohesion, but the change rules of axial strain are different under different subsidence quantities.